V Zarghami; M Ghorbani; MA Shokrgozar; K P Bagheri
Abstract
AbstractThe main causes of bone implant failure are infection and formation of biofilm on the surface of bone implants and increased resistance to antibiotics, lack of proper implant-bone interaction, very small displacements during loading and aseptic loosening. In the present review, we discuss different ...
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AbstractThe main causes of bone implant failure are infection and formation of biofilm on the surface of bone implants and increased resistance to antibiotics, lack of proper implant-bone interaction, very small displacements during loading and aseptic loosening. In the present review, we discuss different types of coatings to eliminate these problems and also explain the future research directions. Application of coatings resulting from bone morphogenetic proteins (BMPs) and coatings with the ability of controlled drug release are among new technologies developed in this field. It is predicted that future belongs to coatings that are capable of topically treating infection, controling aseptic loosening, and resolving the lack of interaction.
